Why Histology Matters
Histology reveals what symptoms, biomarkers, and endoscopy alone cannot. In GI trials, it provides direct evidence of inflammation, healing, structural changes, and treatment response — critical for demonstrating biological effect across indications such as IBD, EoE, celiac disease, and microscopic colitis.
Histology Can Assess:
- Inflammatory infiltrates and immune activity
- Epithelial injury, mucosal integrity, and repair
- Fibrosis, extracellular matrix remodeling, and architectural distortion
- Disease activity and treatment response
Fully Integrated Histology Support, From Biopsy to Insight
Alimentiv unifies histology, histopathology, and digital pathology, delivering consistent, blinded, and compliant central review for high confidence tissue endpoints.
Our histology services include:
- Protocol‑aligned biopsy acquisition
- Tissue processing & staining at the AcelaBio Histopathology Lab
- Expert histopathologic interpretation by our trained readers
- Digital review, scoring, and reporting through Lucidity™ and Notō
- Alimentiv unifies histology, histopathology, and digital pathology — delivering consistent, blinded, and compliant central review for high‑confidence tissue endpoints
Digital Pathology Central Review
Alimentiv offers standardized, blinded review of digitized histology slides through Lucidity™, our proprietary tissue management platform designed for secure, compliant handling of whole-slide images.
Developed in partnership with international expert GI pathologists and leading imaging software developers, Alimentiv provides a distinctive and competitive service for centralized histological assessment of disease activity, starting at tissue processing and digitization of slides.
Scoring Indices:
- Geboes Score
- Robarts Histopathology Index (RHI)
- Nancy Histological Index (NHI)
- Pouchitis Disease Activity Index (PDAI)
- Global Histological Disease Activity Score (GHAS)
- Eosinophilic Esophagitis Histological Scoring System (EoEHSS)
- Peak Eosinophil Count (PEC)
